{"id":7122,"date":"2018-04-06T14:25:41","date_gmt":"2018-04-06T12:25:41","guid":{"rendered":"http:\/\/www.intalent.udc.es\/ana-rey-rico\/"},"modified":"2018-04-06T14:25:41","modified_gmt":"2018-04-06T12:25:41","slug":"ana-rey-rico","status":"publish","type":"page","link":"https:\/\/www.intalent.udc.gal\/gl\/investigadores-2\/ana-rey-rico\/","title":{"rendered":"Ana Rey Rico"},"content":{"rendered":"

[vc_row row_mask_bg=”” row_arrow=”” el_class=”p-140-cont pb-0″ css=”.vc_custom_1494861745759{margin-top: 0px !important;margin-bottom: 0px !important;}”][vc_column width=”2\/3″][vc_custom_heading text=”Ana Rey-Rico” font_container=”tag:h2|font_size:45px|text_align:left|line_height:1″ google_fonts=”font_family:Lato%3A100%2C100italic%2C300%2C300italic%2Cregular%2Citalic%2C700%2C700italic%2C900%2C900italic|font_style:300%20light%20regular%3A300%3Anormal” cms_custom_headding_type=”heading-borderleft-textbold” css=”.vc_custom_1522146795102{margin-bottom: 0px !important;}”][\/vc_column][vc_column width=”1\/3″][\/vc_column][\/vc_row][vc_row el_class=”p-140-cont pb-0″ css=”.vc_custom_1440603786345{margin-bottom: 100px !important;background-color: #ffffff !important;}”][vc_column][vc_empty_space height=”15px”][vc_row_inner equal_height=”yes” content_placement=”middle” cms_row_inner_overflow=””][vc_column_inner width=”1\/4″][vc_single_image image=”6995″ img_size=”full” alignment=”center” vc_none_hover_effect=””][vc_column_text css=”.vc_custom_1529508611443{padding-left: 25% !important;}”]\"\"<\/a>\"\"<\/a>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/12″ offset=”vc_hidden-xs”][\/vc_column_inner][vc_column_inner width=”2\/3″][vc_column_text]Ana Rey-Rico \u00e9 licenciada en Biolox\u00eda (rama Molecular e Biotecnolox\u00eda) pola Universidade de Santiago de Compostela. En 2011 doutorouse en Farmacia pola mesma Universidade baixo a supervisi\u00f3n dos profesores Carmen \u00c1lvarez-Lorenzo e Anxo Concheiro. O seu proxecto de tese baseouse no uso de copolimeros e o dese\u00f1o de nanotransportadores de f\u00e1rmacos capaces de evadir as bombas de eflujo en terapia do cancro e actuar como sistemas de gelificaci\u00f3n in situ en rexeneraci\u00f3n \u00f3sea.<\/span><\/p>\n

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Tras finalizar o seu doutoramento uniuse como investigadora postdoctoral en terapia g\u00e9nica ao grupo dos profesores Magali Cucchiarini e Henning Madry no Centro de Ortopedia Experimental en Homburg\/ Saarland (Alema\u00f1a). As s\u00faas investigaci\u00f3ns centr\u00e1ronse na utilizaci\u00f3n de biomateriales polim\u00e9ricos como sistema de liberaci\u00f3n controlada de vectores virales recombinantes adeno-asociados ( rAAV) en rexeneraci\u00f3n da cartilaxe articular. En leste mesmo centro, de 2016 a 2017, foi investigadora principal dun proxecto baseado na liberaci\u00f3n controlada de rAAV a partir de pol\u00edmeros termo-sensibles subvencionado pola Axencia Alem\u00e1 de Investigaci\u00f3n.<\/span><\/p>\n

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Ao longo da s\u00faa carreira investigadora ha publicado m\u00e1is de corenta artigos cient\u00edficos, a maior\u00eda deles nos \u00e1mbitos de biomateriales e tecnolox\u00eda farmac\u00e9utica, dous cap\u00edtulos de libro e alg\u00fans dos seus resultados de investigaci\u00f3n foron protexidos con d\u00faas patentes. Durante este tempo recibiu distintas distinci\u00f3ns como a bolsa HOMFOR outorgada pola Universidade de Saarland e o premio Julian Sanchez Freire da Real Academia de Farmacia de Galicia.<\/span>[\/vc_column_text][\/vc_column_inner][vc_column_inner][vc_empty_space height=”15px”][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_mask_bg=”” row_arrow=”” css=”.vc_custom_1494861130580{background-color: #f4f4f4 !important;}”][vc_column][vc_empty_space height=”15px”][vc_empty_space height=”15px”][vc_row_inner][vc_column_inner width=”1\/2″][vc_custom_heading text=”Proxecto” font_container=”tag:h3|font_size:35px|text_align:left|line_height:1″ google_fonts=”font_family:Lato%3A100%2C100italic%2C300%2C300italic%2Cregular%2Citalic%2C700%2C700italic%2C900%2C900italic|font_style:300%20light%20regular%3A300%3Anormal” cms_custom_headding_type=”heading-borderleft-textbold” css=”.vc_custom_1493987604000{margin-bottom: 0px !important;}”][vc_empty_space height=”15px”][\/vc_column_inner][vc_column_inner width=”1\/2″][\/vc_column_inner][vc_column_inner][vc_column_text]O proxecto de investigaci\u00f3n de Ana Rey-Rico c\u00e9ntrase na obtenci\u00f3n de matrices activadas por xenes mediante unha combinaci\u00f3n de vectores de transferencia g\u00e9nica non virales e biomateriales adaptados para a rexeneraci\u00f3n de cartilaxe.<\/span><\/p>\n

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A terapia g\u00e9nica baseada en vectores non virales constit\u00fae un m\u00e9todo seguro para estimular a rexeneraci\u00f3n de cartilaxe mediante a subministraci\u00f3n definida de xenes que codifican para factores terap\u00e9uticos espec\u00edficos deste tecido. Non obstante a utilizaci\u00f3n destes vectores est\u00e1 principalmente limitada pola s\u00faa baixa eficiencia de transfecci\u00f3n debida principalmente \u00e1 existencia de barreiras fisiol\u00f3xicas e celulares e \u00e1 propia tendencia destes vectores \u00e1 agregaci\u00f3n.<\/span><\/p>\n

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Un enfoque potencial para superar estes obst\u00e1culos \u00e9 a administraci\u00f3n dos vectores mediante o uso de biomateriales polim\u00e9ricos capaces de soslayar estas barreiras e permitir unha liberaci\u00f3n controlada da informaci\u00f3n xen\u00e9tica nas dianas seleccionadas. Neste sentido, o dese\u00f1o de sistemas de liberaci\u00f3n controlada de xenes pode levar a un incremento da produci\u00f3n de marcadores celulares espec\u00edficos que estimulen os procesos de reparaci\u00f3n de cartilaxe no lugar da lesi\u00f3n.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=”15px”][vc_empty_space height=”15px”][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=”35px”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

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